Biological Data Computation Support

Biological Data Computation Support

Work Location: Fort Detrick, MD

Eagle Health is seeking Biological Data Computation Support to join our team in Fort Detrick, MD.

Core Duties:

• Collect the data generated from high-content imaging platform and in collaboration with the Information Technology team support the generation of a database that will capture all the relevant metadata generated from the high-throughput screens
• Capture and integrate the biological and small molecule chemical data to support data entry into the database and provide expertise in assessments of the data that will enable down selecting drug candidates and drive the therapeutic product development against biothreat agents
• Assess the workflow of high-throughput screening platforms and identify the requirements and relevant fields to capture the chemical and biological data attributes that will support the configuration of a searchable database
• Support migration of the screening, chemical, and absorption, distribution, metabolism, and excretion (ADME) data into the database and management of the data in the database, while providing first in class analytical and reporting tools to drive decisions of down selecting promising small molecules for product development
• Perform self-directed exploration and analysis of the dataset generated from the phenotypic screens, including use of relevant R packages, spreadsheets, graphics, and statistical programs that will help predict the behavior of a complex biological system or mechanistic basis for physiological and pathological responses to infection or therapeutic treatment, and that can be employed to design of the new or better drugs that are specific to the pathogen
• Apply their computational skills and biological background to develop computational tools that will support better approaches to integrate the screening data and metadata associated with the biological assays or chemical compounds
• Communicate experimental data, laboratory, or other work-related issues to the appropriate point of contact (POC) and communicate with vendors for technical support and troubleshooting laboratory equipment with assigned space
• Assist in the reporting and communication of the test results, and preparation of technical reports, standard operating procedures, and manuscripts
• Present research findings at least one scientific conference per year, if required, which may require CONUS and/or OCONUS travel and will present results in written and oral format publicly and internally
• Prepare and provide the technical POC (TPOC) a Biological Data Research Technical progress report no later than (NLT) the last day of each month
• Present research findings/presentations at monthly lab meetings and attend scientific discussion weekly meetings