New 
Scientist
 Spectraforce Technologies | |
 United States, Massachusetts, Worcester | |
 Apr 17, 2025 | |
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Job Title: Scientist
Location: Worcester, MA Duration: 12 months Description: Biologics Developability Screening and Automation The Biologics CMC Developability team is an integral part of the Biologics CMC Drug Product Development organization. The Biologics CMC Developability team is responsible for- (1) the identification of biophysical- and chemical liabilities in discovery-stage biologic drug candidates to guide lead selection, and (2) for characterization of the key CMC attributes important for biologic drug development. We have an exciting opportunity for a motivated scientist to join the Client's Biologics CMC Developability team based in Worcester, MA. Key Responsibilities: * Perform in-depth LC-MS based characterization of therapeutic biologic molecules and their post-translational modifications. * Conduct biophysical and biochemical characterization of biologic drug candidates, as needed. * Execute experimental protocols, collect results, and perform data analysis carefully and independently. * Maintain excellent documentation of work including electronic lab notebook and protocols. * Prepare and deliver concise scientific presentations of experimental results. * Oversee maintenance of key laboratory equipment and routine laboratory operations. * Build strong relationships with other team members and across groups. * Understand and adhere to corporate standards regarding code of conduct, safety, and documentation compliance. Qualifications: * BS or MS in Biochemistry, Biology, Chemistry (or equivalent, e.g., Chemical Engineering, Pharmaceutical Sciences) with 5+ (BS) or 2+ years (MS), or Ph.D. with 0+ years of biopharmaceutical industry experience. Candidates with less than 5 years/ BS will be considered for Scientist II-3-5 years/BS Hands-on experience with protein mass-spectrometry (subunit analysis, peptide mapping, disulfide mapping). * Experience with biochemical and biophysical characterization of biologic proteins would be preferred. * Experience with liquid handling robots and their programming would be highly beneficial. * Demonstrated track record of independent thinking, creativity, and scientific accomplishment. * Highly responsible and self-motivated. Skills to plan and conduct experiments with high quality and timely deliverables. Able to perform data analysis using MS Excel & GraphPad. * Team player with excellent collaboration and communication skills. | |