Project Scientist - Human Genetics - Reue Lab

Applications are sought for a full-time Assistant Project Scientist position, with a focus on research in cardiometabolic disease using mouse models, cell culture studies, and 'omics data generation and analysis. The successful candidate will work as part of an interdisciplinary research team in the laboratory of Dr. Karen Reue in the UCLA Department of Human Genetics and the Metabolism Theme Area. The Reue lab conducts studies aimed at elucidating the basis of sex differences in obesity, fatty liver, postprandial lipid metabolism, exercise biology, and atherosclerosis using mouse models to interrogate the role of sex chromosome dosage and gonadal sex as determinants of these traits.

Experience is required with experimental techniques that animal physiology, modulation of gene expression in vivo and in vitro, and 'omics datasets (e.g., bulk and single cell RNA-seq, ATAC-seq, CUT&RUN, lipidomics, proteomics, and DNA methylomics). The ideal candidate will have an interest in pursuing projects that aim to identify the contributions of chromosomal and gonadal sex determinants to cardiometabolic disease conditions ranging from the in vivo phenotype to the molecular basis for observed sex differences. The candidate should be experienced in, or motivated to learn, computational methods for the interpretation of 'omics data, and should be enthused to work as a team member within the lab to execute projects in the most efficient and rigorous manner. The candidate should also have experience and demonstrated ability in scientific writing of research manuscripts.

A successful candidate will have the following qualifications:

* PhD in a biological discipline

* Postdoctoral experience in mouse physiology, molecular biology, and analysis of 'omics datasets

* Ability to work in a collaborative interdisciplinary environment

* Desire to conduct research to enhance the understanding of how biological sex influences cardiometabolic health and disease

Ph.D.

First-author publication and additional co-author publications

• 2 required (contact information only)

Please provide the names and contact information of 2 references.

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct, are currently being investigated for misconduct, left a position during an investigation for alleged misconduct, or have filed an appeal with a previous employer.

• "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.
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