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Deputy Director, Tuberculosis Vaccines

Bill and Melinda Gates Foundation
paid time off
United States, Washington, Seattle
500 5th Avenue North (Show on map)
Jul 01, 2025

The Foundation

We are the largest nonprofitfighting poverty, disease, and inequity around the world. Founded on a simple premise: people everywhere, regardless of identity or circumstances, should have the chance to live healthy, productive lives. We believe our employees should reflect the rich diversity of the global populations we aim to serve. We provide an exceptional benefits package to employees and their families which include comprehensive medical, dental, and vision coverage with no premiums, generous paid time off, paid family leave, foundation-paid retirement contribution, regional holidays, and opportunities to engage in several employee communities. As a workplace, we're committed to creating an environment for you to thrive both personally and professionally.

The Team

Our Global Health (GH) division harnesses advances in science and technology to save lives in developing countries. We focus on the health problems that have a major impact in developing countries but get too little attention and funding. Where tools exist, we support sustainable ways to improve their delivery. Where they don't, we invest in research and development of new interventions, such as vaccines, drugs, and diagnostics. Our work in infectious diseases focuses on strategies to fight and prevent HIV/AIDS, malaria, tuberculosis (TB), neglected tropical diseases, enteric and diarrheal diseases, pneumonia and maternal, newborn and child health.

Our TB and HIV work is combined under a joint TB/HIV Program Strategy Team (PST) which focuses on research, development and delivery of new products and tools.

The foundation's TB team aims to address key gaps along the TB care pathway through new approaches to protecting against infection, preventing progression from infection to disease, and improving diagnosis and treatment. Our efforts are diversified based on the understanding that vaccines, diagnostics, drugs, and improved care delivery are all essential to addressing the TB epidemic. Our strategy places considerable emphasis on the discovery and development of new TB vaccines.

We focus our HIV efforts on some of the countries hardest hit by HIV in sub-Saharan Africa (SSA), particularly in populations at greatest risk of infection, including adolescent girls and young women. While treatment scale-up has led to significant declines in new infections and mortality, the rate is not rapid enough to reach globally agreed targets and there remains persistently high incidence and mortality in several countries in SSA. The HIV team's strategic vision is to accelerate the reduction in the incidence of HIV infection in high-burden geographies and populations, with a focus on the development of new and affordable prevention and treatment interventions, including long-acting drugs, vaccines and biologics, and to enable their effective use.

Application Deadline: Friday, July 18, 2025

Your Role

You shape and manage the execution of the TB Vaccine strategy. You manage relationships with grantees, contractors, and key partners to achieve the foundation's desired impact, provide project briefings/updates to foundation leadership, and represent the foundation in meetings with external partners and at scientific conferences/workshops.

What You'll Do

  • Lead, shape, and guide strategy to support the foundation's large and diverse TB vaccine portfolio, including needs assessments, strategic prioritization across product concepts, advancement of lead candidates, clinical development planning, and impact measurement of product solutions towards approved strategic objectives.

  • Oversee the design and implementation of a portfolio of high-impact TB vaccine grants, including support to robust systems that ensure grantee collaboration, balance in the portfolio, and effective annual planning.

  • Identify and cultivate robust partnerships within a broad and diverse global eco-system to achieve impact (i.e., pharma, biotech, vaccine manufacturers, academia, product development partners, and governments).

  • Act as a leadership and thought partner to grantees, helping them achieve strategic objectives.

  • Lead and guide the TB Vaccine team's efforts in optimizing the level of engagement required for specific team and grantee support.

  • Provide strategic guidance in crafting grants or contracts, helping to ensure that Global Health resources are efficiently and expertly applied.

  • Provide rigorous reviews of TB vaccine development programs that incorporate contributions from both internal and external partners, and anticipate mid-course corrections, project impact, and propose appropriate changes.

  • Support TB Vaccine goal achievement, creating systems to track progress and ensure accountability.

  • Serve as a resource to foundation leadership and programmatic staff on issues related to pre-clinical and clinical TB vaccine development.

  • Act as a foundation representative to key program-related external constituencies, as appropriate, on committees related to area of expertise and responsibilities of the position.

  • Responsible for hiring and managing the talent needed to achieve the foundation's goals.

  • Foster enabling conditions for talent to thrive and be accountable for inclusive team culture.

  • Model and coach equitable decision-making, inclusive behaviors, and actions; address issues in a timely fashion.

Your Experience

  • An MD/PhD or equivalent demonstrated experience, preferably in infectious diseases, vaccine sciences, or microbiology.

  • Extensive experience in a relevant product and clinical vaccine development, including research and intervention.

  • Demonstrated experience with tuberculosis pathogenesis and/or clinical care and/or product development.

  • Extensive experience managing administrative and fiduciary responsibilities.

  • Comprehensive experience in scientific writing and data analysis.

  • Demonstrated experience interacting with regulators in all geographic regions.

  • Demonstrated experience in scientific writing and data analysis.

  • Demonstrated experience advocating and communicating with a broad and diverse audience.

  • Mastery level knowledge of end-to-end clinical vaccine development processes in an industry setting with different vaccine platforms (i.e., viral, microbial and/or mammalian protein, viral vector, mAb, etc.).

  • Mastery level knowledge of clinical research and/or vaccine development in infectious diseases, preferably tuberculosis.

  • Mastery level product development knowledge, including the ability to think through a product development lens and/or collaborate effectively with clinical development partners.

  • Mastery level knowledge of the global health landscape, including an understanding of the complexities of in-country programmatic work.

  • Mastery level knowledge of the interdependencies of research, technical development, manufacturing, supply chain, quality, preclinical, clinical, and regulatory functions in the industry.

  • Ability to travel up to 30% domestically and internationally.

The salary range for this role is $ 293,200.00 to $ 454,400.00 USD. We recognize high-wage market differences in Seattle and Washington D.C., where our offices are located. The range for this role in these locations is $ 319,500.00 to $ 495,300.00 USD. As a mission-driven organization, we strive to balance competitive pay with our mission. New hires salaries are typically between the range minimum and the salary range midpoint. Actual placement in the range will depend on a candidate's job-related skills, experience, and expertise, as evaluated during the interview process.

Hiring Requirements

As part of our standard hiring process for new employees, employment will be contingent upon successful completion of a background check.

Candidate Accommodations

If you require assistance due to a disability in the application or recruitment process, please submit a request here.

Inclusion Statement

We are dedicated to the belief that all lives have equal value. We strive for a global and cultural workplace that supports ever greater diversity, equity, and inclusion - of voices, ideas, and approaches - and we support this diversity through all our employment practices.

All applicants and employees who are drawn to serve our mission will enjoy equality of opportunity and fair treatment without regard to race, color, age, religion, pregnancy, sex, sexual orientation, disability, gender identity, gender expression, national origin, genetic information, veteran status, marital status, and prior protected activity.

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