AVP / VP Compound Profiling & Logistics

Incyte is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value.

The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.

Job Summary (General Purpose of the Job)

The Vice President, (Compound Profiling and Logistics) will be a member of the discovery leadership team and provide strategic leadership and oversight for the high-throughput screening, compound profiling and logistics within the drug discovery organization. This position sits at the intersection of chemistry, antibody discovery and pharmacology and is key to the advancement of new therapies.

Essential Functions of the Job (Key responsibilities)

* Work collaboratively across multiple functional groups within drug discovery to align strategies and ensure seamless operation of compound logistics, early discovery sciences, and data management throughout the drug discovery process.

* Lead a team of multidisciplinary scientists (chemists, biochemists, biologists, computational) fostering a collaborative and innovative environment.

* Oversee and optimize workflows related to compound acquisition, storage, inventory management, quality control, and distribution, ensuring high standards of efficiency, traceability, and compliance.

* Define and implement a robust strategy for the management and screening of both small molecules and biologics, aligned with the organization drug discovery pipeline and goals.

* Integrate the medicinal chemistry, biochemistry, and cellular assay workflows to optimize the use of compound libraries and streamline the Hit Identification, Lead Identification and Lead Optimization processes.

* Centralize and coordinate the activities to develop, validate, and optimize fit-to-purpose cellular and biochemical assays streamlining the early drug discovery process.

* Direct and expand the company's screening capabilities, leveraging automation tools and advanced technologies like virtual screening and AI to accelerate the identification of promising drug candidates.

* Oversee, integrate, and optimize the data acquisition, storage, and distribution workflow, leveraging electronic notebook platforms, computational capabilities, and automation.

* Manage budgets, timelines, and resources effectively to ensure timely delivery of compounds and achieve project and company goals.

* Contribute with writing of regulatory documents for drug filling.

Qualifications (Minimal acceptable level of education, work experience, and competence)

* Ph.D. in Pharmacology, Cancer Biology, Immunology, Chemistry, or a related field, or equivalent experience. Candidates with diverse educational backgrounds and relevant experience are encouraged to apply.

* Experience in the pharmaceutical or biotech industry is preferred.

* A deep understanding of compound management best practices, inventory systems, automated processes, robotic instrumentation, and various screening technologies (e.g., biochemical, cellular assays).

* Understanding of relevant regulatory guidelines, particularly those related to compound handling and safety protocols.

* Strong understanding of medicinal chemistry principles and their application in hit identification and lead optimization campaigns.

* Familiarity with the management of electronic notebooks and data flow in drug discovery.

* Proven track record of building and leading successful teams, with strong communication, interpersonal, and motivational abilities.

* Ability to develop and execute strategic plans, identify and mitigate risks, and troubleshoot complex technical and logistical challenges.

* Excellent written and oral communication skills to effectively interact with colleagues with multiple scientific and non-scientific backgrounds.

* Expertise with all aspects of designing, integrating, deploying, and maintaining data-driven high-availability high-throughput laboratory automation systems

* Expertise managing the full life cycle of capital projects from conceptualization, process development and workflow design, budgetary development, budgetary approval, suppler management, requirements and system documentation to on-time/on-budget execution and reporting

Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.

Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.

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