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Instrumentation Software Engineer

Roche Holdings Inc.
$142,500-264,700
United States, California, Santa Clara
2801 Scott Boulevard (Show on map)
Oct 25, 2025

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

Roche Sequencing is developing ground-breaking next-generation sequencing products that allow scientists/clinicians powerful new avenues to investigate DNA, the blueprint of any lifeforms, in days, giving them the ability to understand health conditions such as cancer, HIV, COVID19 and more! We are not only changing science but changing lives through the development of frontier technologies that accelerate personalized healthcare.

As a member of our Instrument Control Group, you will have the opportunity to work with experts in each of these fields, focused on the common goal of bringing our sequencing platform to market.

The Opportunity:

  • Design and develop high-quality, documented C++ and Python code. This includes implementing low-level instrument control as well as orchestrating complex scientific workflows across the hardware subsystems

  • Directly participate in the mechanical and electrical testing and software integration of various instrument components, including pumps, valves, robotics, temperature sensors, cameras, and more

  • Partner closely with hardware, systems integration, and scientific teams to define requirements, troubleshoot complex issues, and ensure seamless system operation.

  • Perform detailed analysis of system performance, develop software performance metrics, and make recommendations for improvements

  • Collaborate on requirements, architecture, and design of the instrument control software, creating clear, concise design documentation and specifications

Who You Are:

  • You have a Bachelor's degree or higher in Computer Science, Computer Engineering, Electrical Engineering, or a related technical field

  • You have 5+ years of software development experience with exposure to instrument control programming

  • You have strong programming proficiency in C++ and Python

  • You are proficient in a Linux development environment

  • You have a solid understanding of multi-threaded programming, real-time control algorithms, and concurrent systems

  • You have excellent analytical and problem-solving skills, with a proven ability to debug complex issues at the software/hardware interface

  • You have knowledge of core software engineering concepts, object-oriented programming, and the software development life cycle

  • You have experience with message passing design patterns

  • You have experience with version control systems (Git) and issue tracking tools (Jira)

Preferred Qualifications:

  • Background in gene sequencing, biotech instrument design, or working within an FDA-regulated production environment

The expected salary range for this position based on the primary location of Santa Clara ,CA is $142,500-264,700. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.

This position also qualifies for the benefits detailed at the link provided below.

Benefits

Relocation benefits are not available for this position.

Who we are

A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let's build a healthier future, together.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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