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PATH current employees - please log in and apply Here PATH is a global nonprofit dedicated to achieving health equity. With more than 40 years of experience forging multisector partnerships and with expertise in science, economics, technology, advocacy, and dozens of other specialties, PATH develops and scales up innovative solutions to the world's most pressing heath challenges. PATH is seeking an exceptional Senior Program Officer to serve as an analytical partner in supporting transformative cross-organizational initiatives that maximize global health impact. The Senior Program Officer drives complex cost-effectiveness analyses, refines methods with technical experts, and delivers evidence that informs initiative prioritization and donor engagement. This position influences project and portfolio priorities and supports organization-wide strategies. As Senior Program Officer, you will support senior leadership to source, evaluate, prioritize, and secure funding for high-impact, cross-cutting health initiatives that generate significant returns on investment. You will serve as the critical link between program teams, and cost-effectiveness evidence, translating complex technical work into compelling funding proposals that align donor priorities with PATH's strategic opportunities. This is an ideal role for someone with an analytical mind, diplomatic skills, and passion for maximizing health outcomes through strategic resource allocation and evidence-based prioritization. Responsibilities Cost-Effectiveness Analysis & Evidence Synthesis (40%)
Conduct cost-effectiveness analyses of cross-cutting global health initiatives, synthesizing evidence from peer-reviewed literature, program data, and inputs from regional teams and external experts to assess impact per dollar. In collaboration with senior leadership, develop and apply standardized analytical approaches to compare expected health and economic outcomes across interventions and geographies, drawing on principles of applied economics and quantitative evaluation. Model the potential health and economic impact of initiatives at scale, assessing key assumptions, uncertainty, and sensitivity using econometric and counterfactual analysis. Translate complex analytical findings into clear, decision-relevant insights for donors, senior leadership, and program teams, articulating trade-offs and implications for resource allocation.
Strategic Initiative Identification & Portfolio Management (30%)
Work across PATH's health area teams, disease-specific programs, and partnership units to identify high-potential, cross-cutting initiatives with strong prospects for scale and cost-effective impact. Apply structured prioritization frameworks to evaluate initiatives based on cost-effectiveness, scalability, donor alignment, and organizational capacity, informed by economic concepts such as opportunity cost and marginal returns. Support senior leadership in developing and maintaining a portfolio of investment-ready initiatives, including defining value propositions, implementation pathways, and resource requirements. Conduct landscape analyses to identify gaps and opportunities where targeted investment can address systemic inefficiencies, informed by applied microeconomic concepts such as market failures and externalities.
Donor Mapping & Partnership Development (25%)
Support mapping cross-cutting initiatives onto specific donor portfolios, priorities, and funding mechanisms. Support the development of tailored funding proposals that frame PATH's work through a cost-effectiveness and value-for-money lens aligned with donor priorities.
Cross-Organizational Coordination & Communication (5%)
Support organization of regular reviews of the initiative portfolio with relevant program teams and leadership. Synthesize complex analytical and economic information into presentations, reports, and strategic communications for internal and external audiences. Track and report on initiative progress, funding status, and impact metrics.
Required Skills & Experience
Bachelor's degree or higher in Economics, Health Economics, or a closely related quantitative discipline with substantial training in econometrics and applied economic analysis. Minimum 5-7 years of progressively responsible experience in global health, international development, or related fields Demonstrated experience conducting cost-effectiveness analyses, health economic evaluations, or impact assessments in global health or development contexts. Experience working across organizational boundaries in complex, matrix environments Located and working in the US, we will not accept any applications from outside of the US for this role, nor will this role support relocation.
Technical Skills
Strong quantitative and analytical capabilities, including applied econometric analysis, cost-effectiveness modeling, and proficiency in statistical software such as R, Stata, or equivalent tools. Ability to conduct rigorous literature reviews and synthesize evidence from diverse sources Exceptional skills in data visualization and translating complex analyses into clear insights
Personal Attributes & Competencies We are seeking candidates who can be described as:
Insightful: You draw cogent conclusions from large amounts of analysis, distilling what matters most for real-world decision-making and resource allocation Strategic: You see connections across programs and disciplines, identifying opportunities for synergy and catalytic investment Analytical yet Practical: You balance rigor with pragmatism, knowing when to dig deeper and when to move forward with available information Diplomatic: You navigate diverse stakeholder environments with grace, building trust with program teams, senior leadership, and external partners Results-Oriented: You take ownership of outcomes, demonstrating judgment in prioritizing efforts to maximize impact Intellectually Curious: You have a genuine desire to understand why interventions work, what drives costs, and how systems can be transformed Rigorous: You take pride in producing analysis that can withstand scrutiny from technical experts and donor organizations Communicative: You tailor your message to different audiences, whether presenting to epidemiologists or foundation executives
Additional Skills - Exceptional written and verbal communication skills, with ability to craft compelling narratives - Proven ability to work independently, set priorities, and deliver results in fast-paced environments - Strong project management capabilities with attention to detail and deadline management - Collaborative mindset with ability to influence without authority Preferred Qualifications
Postgraduate training in health economics, epidemiology, or related quantitative discipline Experience working in or supporting programs in low- and middle-income countries Familiarity with major global health donors Experience with program monitoring, evaluation, and learning frameworks Knowledge of effective altruism principles and impact-focused philanthropy Track record of publications or presentations on cost-effectiveness or global health priority-setting Experience working remotely and managing distributed teams
What We Offer
Opportunity to shape strategic direction and resource allocation across a leading global health organization Exposure to diverse health programs spanning infectious diseases, maternal/child health, NCDs, and health systems strengthening Direct interaction with senior leadership, program experts, and major philanthropic partners Professional development support and opportunities for continued learning Competitive compensation and comprehensive benefits package Commitment to work-life balance and flexible work arrangements Collaborative, mission-driven organizational culture
To be selected, you must have legal authorization to work in the US PATH is a nonprofit organization that creates a culture of collaboration and partnership. Learn more about the impact you can make globallyhere. For U.S. Based Candidates We offer our employees a competitive salary and generous benefits. For candidates based in the U.S., the annual salary range for this position is $88,000 - $110,000 USD. The final salary is based on a variety of objective factors.
PATH provides a comprehensive benefit package that includes 15 vacation, 10 holiday, 2 personal, and 12 sick days per year; medical and dental plans; life insurance; and disability and retirement benefits. For more details click here.
Hybrid Work
PATH operates within a hybrid workplace model unless otherwise noted. Hybrid employees must reside within commuting distance of one of our PATH offices. PATH's US offices are located in Seattle, WA, and Washington, DC.
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PATH
life insurance, sick time
Feb 25, 2026